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Test Code UPEP Protein Electrophoresis, Urine with monoclonal quantitation (if present) and Immunofixation if indicated (24 hr collection)

Important Note

This test replaces quantitative Bence Jones Protein (QBEN).   A urine immunofixation (IFE) is performed if indicated by pathologist review of electrophoresis scan. 

Requires a 24 hr collection

Additional Codes

Epic Code:  LAB438

Please Note: Additional CPT and professional fee for pathologist’s interpretation may be applied.

Methodology

Includes quantitative total protein, clonal light chains (Bence Jones protein) and intact monoclonal proteins (if present). Result includes clinical interpretation by a pathologist.

If results suggest a presence of Bence Jones protein or monoclonal gammopathy, the clinical pathologist will order an immunofixation electrophoresis

 

Performing Laboratory

Bronson Laboratory Services-Chemistry

Specimen Requirements

Specimen Type: Urine, 24 hour. Entire collection.

Container/Tube: Clean, plastic urine container

Specimen Volume: 30 mL aliquot from well mixed 24-hour urine.

Collection Instructions:

1. No preservative. Refrigerate specimen during collection.

2. Random urine collection is not acceptable.

Additional Information:

1. 24-Hour volume is required.

2. Starting and ending dates/times of collection are required.

3. Follow instructions in Patient Instructions for 24-Hour Collection under Special Instructions.

Processing Instructions:

1. Measure and record total volume.

2. Mix entire collection well and pour off a 30.0 mL aliquot.

Specimen Transport Temperature

Refrigerate

Reference Values

An interpretive report will be provided.

Day(s) Test Set Up

Tuesday, Thursday

Test Classification and CPT Coding

Urine Protein Electrophoresis:  84166

Urine Immunofixation if indicated:  

Special Instructions

BMH Laboratory Only

  1. The proper collection duration and volume entered
  2. A urine cup placed in the 24 hour bin in the Accession refrigerator
  3. A urine cup that is a minimum of 12 mL for wet chemistry placed in the UPEP bin by KWET rack. 
  4. An aliquot poured off into a false bottom tube for a urine total protein for chemistry

 

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