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Test Code LIPD or LAB18 Lipid Panel With Reflex Measured LDL, Serum or Plasma

Important Note

Note: Unless the order specifies "Lipid Panel Without Reflex Measured LDL," the measured LDL will be performed in cases where the triglyceride is >800 mg/dL. This is due to the inability to calculate an LDL if the triglyceride level is >800.

If a reflex-measured LDL is not desired, order LIPN (LAB2211)

Note about fasting requirements: Fasting is no longer required for lipid panels.  See the December 2020 LabWire (Resources section) for details.

There may be cases where a fasting triglyceride level is desired.  If so, the patient should be instructed to fast from food or beverages (other than water) for 12 hours before collecting a sample.  Fasting patients patient should be on a normal diet and maintain a stable weight for one week before testing.  Consuming alcohol or fatty foods up to 24 hours prior to specimen collection can also increase serum triglycerides. 

Profile Information

Test ID Reporting Name Available Separately? Always Performed?
CHOL Cholesterol Y Y
TRIG Triglycerides Y Y
HDL HDL Y Y
LDL, calc LDL - calculated result* N Y*
NonHDL2 Non HDL Chol. (LDL+VLDL) Y Y
Chol/HDL Chol/HDL Ratio Y Y

*LDL is calculated by the NIH (Sampson) formula. If the triglycerides result is > 800 mg/dL, the LDL - calculated result will not be performed. Instead, a measured LDL is reflexed and performed.  See the LabWire 2020 article under "Resources" for additional information. 

Specimen Requirements

Container Type:

Optimal: Gold or Mint*

*For STAT requests

Acceptable: Red or Green
Optimal Collection Volume: 

4.5 mL; full tube
Specimen Minimum Volume:
  • Adults: 1 mL whole blood
  • Neonates: 1 microtainer (400-600 uL)
Collection Instructions:

Gently invert sample 5-6 times after collection.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. If serum, allow the sample to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container.

4. Keep serum/plasma refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum* Room Temperature 2 days
Refrigerated 7 days
Frozen 3 months

*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.

Specimen Rejection Criteria

Hemolysis Mild OK; Moderate OK; Gross Reject
Other Quantity not sufficient

Useful For

Evaluation of risk for and monitoring of atherosclerotic disease.

Methodology

Roche Cobas - Enzymatic colorimetric

Reference Ranges

Cholesterol

Reference Range and Reporting Units Interpretation
< 200 mg/dL Optimal
200-239 mg/dL Borderline high
> 240 mg/dL High

 

Triglycerides

Reference Range and Reporting Units Interpretation
< 150 mg/dL Acceptable
150-199 mg/dL Borderline high
200-499 mg/dL High
> 500 mg/dL Very high

 

HDL Cholesterol

Reference Range and Reporting Units Interpretation
< 40 mg/dL Low
40-59 mg/dL Acceptable
> 60 mg/dL Optimal

 

LDL Cholesterol (Calculated with NIH LDL-C Equation).  See attached notice for details

Reference Range and Reporting Units Interpretation
< 100 mg/dL Optimal
100-129 mg/dL Low Risk
130-159 mg/dL Borderline high
160-189 mg/dL High
> 190 mg/dL Very high

 

Non-HDL Cholesterol

Reference Range and Reporting Units Interpretation
< 130 mg/dL Optimal
130-159 mg/dL Borderline high
160-189 mg/dL High
> 190 mg/dL Very High

 

Cholesterol/HDL Ratio (male)

Reference Range and Reporting Units Risk
3.4 1/2 average
5.0 Average
10.0 2x average
24.0 3x average

 

Cholesterol/HDL Ratio (female)

Reference Range and Reporting Units Risk
3.3 1/2 average
4.4 Average
7.0 2x average
11.0 3x average

Interpretive

LPSC1 - Clinical & Interpretive: Lipid Panel, Serum (mayocliniclabs.com)

Day(s) Performed

24/7

Expected TAT

Same day

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo, Battle Creek, Paw Paw, South Haven

Sample Retention Time

7 days

CPT Code

80061

LOINC Code

100898-6

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