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HelpTest Code LDH or LAB96 Lactate Dehydrogenase (LDH), Serum or Plasma
Specimen Requirements
| Container Type: |
Optimal: Gold or Mint* *For STAT requests |
|
Acceptable: Red or Green |
|
| Optimal Collection Volume: |
4.5mL; full tube |
| Minimum Volume: |
|
| Collection Instructions: |
Gently invert the sample 5-6 times after collection. |
| Specimen Transport: |
Refrigerate |
| Processing Instructions: |
1. If serum, allow the specimen to clot for 30 minutes. 2. Centrifuge specimen within 2 hours of collection. 3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container. 4. Keep the serum or plasma refrigerated until testing can be performed. |
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum* | Refrigerated | 4 days |
| Room Temperature | 7 days | |
| Frozen | 6 weeks |
*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.
Specimen Rejection Criteria
| Hemolysis | Mild OK; Moderate Reject; Gross Reject |
| Lipemia | Mild OK; Moderate OK; Gross Reject |
| Icterus | Mild OK; Moderate OK; Gross Reject |
| Other | Quantity not sufficient |
Useful For
Elevated serum levels of LDH have been observed in various disease states. The highest levels are seen in patients with megaloblastic anemia, disseminated carcinoma, and shock. Moderate increases occur in muscular disorders, nephrotic syndrome, and cirrhosis. Mild increases in LDH activity have been reported in cases of myocardial or pulmonary infarction, leukemia, hemolytic anemia, and non-viral hepatitis.
Methodology
Roche Cobas - UV Assay
Reference Ranges
| Age | Reference Range and Reporting Units |
|---|---|
| Adults | 94-250 U/L |
| 0-4 days | 290-775 U/L |
| 5-10 days | 545-2,000 U/L |
| 11 days to 24 months | 180-430 U/L |
Day(s) Performed
24/7
Expected TAT
Same day
Performing Laboratory
Bronson Laboratory, Chemistry - Kalamazoo, Battle Creek, Paw Paw, South Haven
Sample Retention Time
7 days
CPT Code
83615
LOINC Code
14804-9