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HelpTest Code FSH or LAB86 Follicle Stimulating Hormone (FSH), Serum or Plasma
Specimen Requirements
| Container Type: |
Optimal: Gold or Mint* *For STAT requests |
|
Acceptable: Red or Green |
|
| Optimal Collection Volume: |
4.5mL; full tube |
| Minimum Volume: |
1 mL whole blood |
| Collection Instructions: |
Gently invert the sample 5-6 times after collection. |
| Specimen Transport: |
Refrigerate |
| Processing Instructions: |
1. If serum, allow the specimen to clot for 30 minutes. 2. Centrifuge specimen within 2 hours of collection. 3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container. 4. Keep serum or plasma refrigerated until testing can be performed. |
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum* | Refrigerated | 5 days |
| Room Temperature | 14 days | |
| Frozen | 6 months |
*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.
Specimen Rejection Criteria
| Hemolysis | Mild OK; Moderate OK; Gross Reject |
| Lipemia | Mild OK; Moderate OK; Gross Reject |
| Icterus | Mild OK; Moderate OK; Gross Reject |
| Other | Quantity not sufficient |
Useful For
The determination of FSH together with LH is indicated for congenital diseases with chromosome aberrations, amenorrhea (causes), polycystic ovaries (PCO), and menopausal syndrome.
In men, FSH may be used in conjunction with other clinical findings to evaluate infertility.
Methodology
Roche Cobas - Electrochemiluminescence assay
Reference Ranges
Male
|
Reference Range and Reporting Units |
|
|---|---|
|
Median (mIU/mL) |
2 SD Range (mIU/mL) |
|
4.6 |
1.5-12.4 |
Female
|
Phase |
Reference Range and Reporting Units |
|
|---|---|---|
|
Median (mIU/mL) |
2 SD Range (mIU/mL) |
|
|
Follicular Phase |
6.9 |
3.5-12.5 |
|
Mid Cycle Peak |
12.3 |
4.7-21.5 |
|
Luteal Phase |
3.6 |
1.7-7.7 |
|
Postmenopausal |
67.0 |
25.8-134.8 |
Children (< 10 years)
|
Reference Range and Reporting Units |
|
|---|---|
|
Median (mIU/mL) |
2 SD Range (mIU/mL) |
|
1.6 |
0.2-3.8 |
Interpretive
FSH and LH are generally elevated in:
- Primary gonadal failure
- Complete testicular feminization syndrome
- Precocious puberty (either idiopathic or secondary to a central nervous system lesion)
- Menopause
- Primary ovarian hypofunction in female patients
- Primary hypogonadism in male patients
Normal or decreased FSH in:
- Polycystic ovary disease in female patients
FSH and LH are both decreased in failure of the pituitary or hypothalamus.
Source: Mayo Medical Labs
Day(s) Performed
24/7
Performing Laboratory
Bronson Laboratory, Chemistry - Kalamazoo
Sample Retention Time
7 days
CPT Code
83001
LOINC Code
20433-9