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Test Code UTRI or LAB2105 Tricyclic Antidepressant Screen, Urine

Important Note

Drug screens performed at Bronson Laboratory are for medical purposes only. No chain of custody or specimen adulteration testing is performed. All positive results are presumptive. A presumptive positive means that this screening method is positive. A more specific alternative method must be used to obtain a confirmed analytical result. Confirmatory testing is available on request through our reference lab, Mayo. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly with presumptive positive results.

If employment/legal drug screening is required, contact ProHealth Management Services at 26-341-7547.

Specimen Requirements

Container Type:

Sterile urine cup

 

 
Optimal Collection Volume: 

5 mL
Minimum Volume:

1 mL
Collection Instructions:

1. Collect a random urine specimen from the patient.

2. Ensure the lid is secured tightly before sending it to the lab.

3. Ensure that no preservatives are used.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. Pour off urine into a labeled aliquot tube.

2. Centrifuge the urine aliquot.

3. Deliver the urine aliquot to the chemistry department.

Specimen Stability

Specimen Type Temperature Time
Urine Refrigerated 4 days

Specimen Rejection Criteria

Adulterated urine specimen

Useful For

Screening for the detection of Tricyclic Antidepressants (TCAs).

Methodology

Bio-Rad TOX/See Kit - Lateral flow chromatographic immunoassay

Reference Ranges

Negative

 

Methodology Comment: This assay detects tricyclic antidepressants (Nortriptyline, Nordoxepin, Trimipramine, Amitriptyline, Promazine, Desipramine, Imipramine, Clomipramine, Doxepin, and Maprotiline) at levels ranging from 200 to 3,000 ng/mL (depending on the drug). Extremely high levels of Promethazine may also cause positive results.

Day(s) Performed

24/7

Expected TAT

Same day

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo

Sample Retention Time

7 days

CPT Code

80305

LOINC Code

19312-8