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HelpTest Code UCOT or LAB736 Cotinine, Urine
Specimen Requirements
| Container Type: |
Sterile urine cup
|
| Optimal Collection Volume: |
5 mL |
| Minimum Volume: |
1 mL |
| Collection Instructions: |
1. Collect a random urine specimen from the patient. 2. Ensure the lid is secured tightly before sending it to the lab. 3. Ensure that no preservatives are used. |
| Specimen Transport: |
Refrigerate |
| Processing Instructions: |
1. Pour off urine into a labeled aliquot tube. 2. Centrifuge the urine aliquot. 3. Deliver the urine aliquot to the chemistry department. |
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated | 7 days |
Specimen Rejection Criteria
Quantity not sufficient
Useful For
Detecting cotinine in urine.
Methodology
Roche Cobas - Homogeneous enzyme immunoassay
Reference Ranges
|
Test ID |
Reference Range and Reporting Units |
|---|---|
|
UCOT |
Negative: < 100 ng/mL |
|
Borderline: 100-300 ng/mL |
|
|
Positive: > 300 ng/mL |
Interpretive
Nicotine is rapidly metabolized in the liver to cotinine, which is excreted into the urine. Most tobacco users excrete cotinine in the range of 1,000 ng/mL to 8,000 ng/mL. Following the cessation of nicotine intake, urine cotinine levels become undetectable in 3 days to 2 weeks depending upon the frequency and duration of tobacco use and the hydration and concentration of the urine sample.
Day(s) Performed
24/7
Expected TAT
Same day
Performing Laboratory
Bronson Laboratory, Chemistry - Kalamazoo
Sample Retention Time
7 days
CPT Code
80307
LOINC Code
10366-3