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Test Code TOXOG or LAB501 Toxoplasma gondii IgG, Serum

Important Note

Note: If the Toxoplasma IgG is positive, a reflex test TOXMMR (LAB659) is performed to help determine if the infection is recent. If the Toxoplasma IgM is positive,  Mayo recommends sending the specimen to the Palo Alto Medical Foundation for confirmatory testing. 

Specimen Requirements

Container Type:

Optimal: Gold

Acceptable: Red 

 
Optimal Collection Volume: 

4.5mL; full tube
Minimum Volume:

1 mL
Collection Instructions:

Gently invert the sample 5-6 times after collection.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. Allow the specimen to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. After centrifugation, specimen tubes without a gel barrier should have the serum aliquoted to a false bottom container.

4. Keep serum refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum Refrigerated 7 days
Room Temperature 8 hours

Specimen Rejection Criteria

Hemolysis Mild OK; Moderate OK; Gross Reject
Lipemia Mild OK; Moderate OK; Gross Reject
Icterus Mild OK; Moderate OK; Gross Reject
Other Quantity not sufficient

Useful For

Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii. The presence of IgG antibodies indicates that the individual has been infected with toxoplasma in the past, but the level of reactivity does not indicate how recently the infection occurred.

Methodology

Bio-Rad BioPlex 2200: Multiplex flow immunoassay

Reference Ranges

 Test ID   Reference Range and Reporting Units
TOXOG < 10 IU/mL: Negative
10-11 IU/mL: Equivocal
> 11 IU/mL: Positive

Interpretive

TOXGP - Clinical & Interpretive: Toxoplasma gondii Antibody, IgG, Serum (mayocliniclabs.com)

Day(s) Performed

Monday through Friday

Expected TAT

Same day or 1-2 days

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo

Sample Retention Time

7 days

CPT Code

86777

LOINC Code

8039-0