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Test Code TIB or LAB829 Iron and  Total Iron-Binding Capacity (TIBC), Serum or Plasma

Profile Information

Test ID Reporting Name Available Separately? Always Performed?
FE Iron Y Y
TRANS Transferrin Y Y
TIBC TIBC N Y
Iron Sat % Iron Saturation N Y

Specimen Requirements

Container Type:

Optimal: Gold or Mint*

*For STAT requests

Acceptable: Red or Green
Optimal Collection Volume: 

4.5 mL; full tube
Specimen Minimum Volume:
  • Adults: 1 mL whole blood
  • Neonates: 1 microtainer (400-600 uL)
Collection Instructions:

Gently invert sample 5-6 times after collection.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. If serum, allow the sample to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container.

4. Keep serum/plasma refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum* Room Temperature 7 days
Refrigerated 8 days
Frozen 6 months

*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.

Specimen Rejection Criteria

Hemolysis Mild OK; Moderate Reject; Gross Reject
Lipemia Mild OK; Moderate OK; Gross Reject
Icterus Mild OK; Moderate OK; Gross Reject
Other Quantity not sufficient

Useful For

Screening for hemochromatosis.

Methodology

Roche Cobas

  • FE: Colorimetric
  • TRANS: Immunoturbidimetric

Reference Ranges

 

Test ID Reference Range and Reporting Units
FE Male: 80-160 ug/dL
Female: 60-135 ug/dL
TRANS 200-360 mg/dL
TIBC 254-457 ug/dL
Iron Sat % Male: 20-55%
Female: 15-50%

Interpretive

FEC - Clinical & Interpretive: Iron and Total Iron-Binding Capacity, Serum (mayocliniclabs.com)

Day(s) Performed

24/7

Expected TAT

Same day

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo and Battle Creek

Sample Retention Time

7 days

CPT Code

  • FE: 83540
  • TRANS: 84466

LOINC Code

  • FE: 2498-4
  • TRANS: 3034-6
  • TIBC: 2500-7
  • Iron Sat %: 2502-3

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