Test Code TAPEN Tapentadol and Metabolite, Random, Urine
Useful For
Monitoring of compliance utilizing tapentadol
Detection and confirmation of the illicit use of tapentadol
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Tapentadol and Metabolite, USpecimen Type
UrineAdvisory Information
If submitting for multiple tests on 1 order, submit a total volume of 5 mL per test ordered in a single plastic container.
Specimen Required
Supplies: Aliquot Tube, 5 mL (T465)
Collection Container/Tube: Plastic urine container
Submission Container/Tube: Aliquot Tube, 5 mL (T465)
Specimen Volume: 2 mL
Collection Instructions: No preservative.
Specimen Minimum Volume
0.1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 14 days | |
Ambient | 14 days | ||
Frozen | 14 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
Cutoff: 25 ng/mL
Note: Tapentadol concentrations will be reported quantitatively and N-desmethyltapentadol will be reported qualitatively (Present or Negative).
Day(s) and Time(s) Performed
Tuesday, Thursday; 2nd shift
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80372
G0480 (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
TAPEN | Tapentadol and Metabolite, U | In Process |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
35916 | Tapentadol | 65807-0 |
35917 | N-desmethyltapentadol | 65808-8 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.