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Test Code PBNP or LAB2242 Pro B Natriuretic Peptide (pBNP), Serum or Plasma

Specimen Requirements

Container Type:

Optimal: Gold or Mint*

*For STAT requests

Acceptable: Red or Green
Optimal Collection Volume: 

4.5mL; full tube
Minimum Volume:

1 mL whole blood
Collection Instructions:

Gently invert the sample 5-6 times after collection.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. If serum, allow the specimen to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container.

4. Keep serum or plasma refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum* Refrigerated 6 days
Room Temperature 3 days
Frozen 24 months

*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.

Specimen Rejection Criteria

Hemolysis Mild OK; Moderate OK; Gross Reject
Lipemia Mild OK; Moderate OK; Gross Reject
Icterus Mild OK; Moderate OK; Gross Reject
Other Quantity not sufficient

Useful For

Aids in the diagnosis of individuals suspected of having congestive heart failure.

Methodology

Roche Cobas - Electrochemiluminescence assay

Reference Ranges

Males

Age (years) Reference Range (pg/mL)
< 45 < 93 
45-54 < 138
55-64 < 177
65-74 < 229
> 75 < 852

 

Females

Age (years) Reference Range (pg/mL)
< 45  < 178
45-54 < 192
55-64 < 226
65-74 < 353
> 75 < 624

Interpretive

PBNP1 - Clinical & Interpretive: NT-Pro B-Type Natriuretic Peptide, Serum (mayocliniclabs.com)

Day(s) Performed

24/7

Expected TAT

Same day

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo, Battle Creek, Paw Paw, South Haven

Sample Retention Time

7 days

CPT Code

83880

LOINC Code

33762-6