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Test Code MEPCR Meningitis/Encephalitis PCR, CSF

Important Note

This test is for CSF samples ONLY.

If specimen is a body fluid or non-lesion sample see test LHSV
If specimen is a vesicle or lesion see test HS12VZ.
For Neonatal Screening, see test VHSV.

Infectious

Additional Codes

LAB 2331

Reference Values

Normal Result:  Not Detected or Negative

Abnormal Result:  Detected or Positive

Methodology

Multiplexed Nucleic Acid Test using Filmarray Instrument.

 

Includes detection of:

Eschericia coli K1

Listeria monocytogenes

Neisseria meningitides

Streptococcus agalactiae

Streptococcus pneumoniae

Cytomegalovirus (CMV)

Enterovirus

Herpes simplex virus 1 & 2 (HSV 1 & 2)

Human Herpesvirus 6 (HHV-6)

Human parechovirus

Varicella zoster virus (VZV)

Cryptococcus neoformans/gattii

Specimen Requirements

Specimen Type:  CSF

Container/Tube:  Sterile Tube

Specimen Volume:  200 uL

 

Specimen Transport/Temperature

Refrigerated:  7 days

Ambient:         24 hours

Test Classification and CPT Coding

87798 x 8

Eschericia coli K1

Listeria monocytogenes

Neisseria meningitides

Streptococcus agalactiae

Streptococcus pneumonia

Cryptococcus neoformans/gattii

Human parechovirus

Varicella zoster virus (VZV)

 

87653

Streptococcus agalactiae

 

87532

Human herpes virus-6

 

87529 x 2

Herpes simplex virus 1 & 2

 

87498

Enterovirus

 

87496

Cytomegalovirus (CMV)

 

 

Days Set Up

Monday through Sunday 24/7

Clinical Utility

The FilmArray ME Panel is indicated as an aid in the diagnosis of specific agents of meningitis and/or encephalitis and results are meant to be used in conjunction with other clinical, epidemiological, and laboratory data. Results from the FilmArray ME Panel are not intended to be used as the sole basis for diagnosis, treatment, or other patient management decisions. Positive results do not rule out co-infection with organisms not included in the FilmArray ME Panel. The agent detected may not be the definite cause of the disease. Negative results do not preclude central nervous system (CNS) infection. Not all agents of CNS infection are detected by this test and sensitivity in clinical use may differ from that described in the package insert.

 

The FilmArray ME Panel is not intended for testing of specimens collected from indwelling CNS medical devices.

The FilmArray ME Panel testing is intended to be used in conjunction with standard of care culture for organism recovery, serotyping, and antimicrobial susceptibility testing.

NOTE:  Bacterial cultures of CSF and MEPCR should always be evaluated together. If no BACT LAB897 is ordered with the MEPCR, one will be added by the laboratory.