Important Note

PLEASE NOTE:   If possible, the patient cannot be receiving anticoagulation medication as this will interfere with test results:

• This testing is not appropriate for patients on Rivaroxaban (Xarelto).  That medication  confounds lupus anticoagulant testing because the DRVVT is prolonged in these patients but it also corrects with excess phospholipid, mimicking a lupus anticoagulant. Patient medication review is critical to avoid false-positive findings and inappropriate diagnosis of antiphospholipid syndrome.  If possible, the patient should abstain from this medication for a minimum of 2 days prior to collection of a specimen for this test.
• Other direct Xa inhibitors including Eliquis(apixaban) and direct thrombin inhibitors including Pradaxa (dabigatran), Acova(argatroban) also affect test results.
• Patient should not be receiving warfarin or heparin. If the patient is currently on warfarin or heparin, this should be noted, treatment with heparin causes false-positive results of in vitro coagulation testing for lupus anticoagulant. Warfarin treatment may impair ability to detect the more subtle varieties of lupus-like anticoagulants.