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Test Code CEA or LAB57 Carcinoembryonic Antigen (CEA), Serum

Important Note

Patient Preparation: For 12 hours before this test do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins. Biotin can interfere with many immunoassay tests.

Specimen Requirements

Container Type:

Optimal: Gold

Acceptable: Red 

Optimal Collection Volume: 

4.5mL; full tube

Minimum Volume:

1 mL whole blood

Collection Instructions:

Gently invert the sample 5-6 times after collection.

Specimen Transport:

Refrigerate

Processing Instructions: 

1. Allow the specimen to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. After centrifugation, specimen tubes without a gel barrier should have the serum aliquoted to a false bottom container.

4. Keep the specimen refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum Refrigerated 14 days
Room Temperature 7 days
Frozen 6 months

Specimen Rejection Criteria

Hemolysis Mild OK; Moderate OK; Gross Reject
Lipemia Mild OK; Moderate OK; Gross Reject
Icterus Mild OK; Moderate OK; Gross Reject
Other Quantity not sufficient

Useful For

The main indication for CEA determinations is the follow-up and therapy-management of colorectal carcinoma. CEA determinations are not recommended for cancer-screening in the general population. CEA concentrations within the normal range do not exclude the possible presence of malignant disease.

Methodology

Roche Cobas - Electrochemiluminescence assay

 

Note: Values from different methods may give different results and cannot be used interchangeably.

Reference Ranges

0-5 ng/mL

 

Note: Smokers may have higher values.

Day(s) Performed

24/7

Expected TAT

Same day

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo

Sample Retention Time

7 days

CPT Code

82378

LOINC Code

2039-6