Methodology

Includes serum free light chains (kappa, lambda, ratio, and serum free light chain difference) and serum protein electrophoresis (albumin, alpha-1, alpha-2, beta- and gamma-globulins, total protein, and clinical interpretation by a pathologist). If kappa/lambda ratio is abnormal or result is inconclusive for a monoclonal gammopathy, the clinical pathologist will order an immunofixation electrophoresis. 

Please see the LabWire Article (link at left under Resources) for additional information.