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Test Code RPRTX or LAB3348 RPR Response to Therapy Titer or Immigration Exam, Serum

Important Note

This test is not intended to be used as a screening test. Instead, please order RPRB (LAB3359) and/or reference Bronson's Syphilis Reverse Algorithm for more information. 

RPR Response Titers (RPRTX) are intended to be used in the following situations:

  1. For therapy monitoring on patients with previously positive RPR or Syphilis results. 
  2. For Immigration examination testing that specifies RPR testing only.

Specimen Requirements

Container Type:

Optimal: Gold

Acceptable: Red
Optimal Collection Volume: 

5 mL
Minimum Volume:

2 mL
Collection Instructions:

Gently invert the sample 5-6 times after collection.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. Allow the sample to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. Separate serum into a false bottom container.

4. Keep serum refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum

Refrigerated

 5 days

Specimen Rejection Criteria

Quantity not sufficient

Useful For

RPR response to therapy should be requested to monitor patient treatment of previously positive results. This test may also be requested for immigration examination where the RPR-only testing is specified.

Methodology

Coagglutination

Reference Ranges

RPR Titer

< 1:2

1:2

1:4

1:8

1:16

1:32

1:64

> 1:64

Day(s) Performed

Monday, Wednesday, and Friday - Day shift

Expected TAT

Same day or 1-2 days

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo

Sample Retention Time

7 days

CPT Code

  • RPR - 86592
  • RPR Titer (performed if RPR is reactive) - 86593

LOINC Code

31147-2

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