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Test Code PSAS or LAB2391 Total Prostate-Specific Antigen, Screen, Serum or Plasma

Important Note

Total Prostate-Specific Antigen has two order codes based on the order diagnosis of the patient. The PSAS (LAB2391) should be ordered for routine screening when the patient has no history of prostate cancer. 

  • For patients diagnosed with prostate cancer or elevated total PSA result(s), please order PSAM (LAB2390). 

Methodology note: Total PSA is performed on the same reagent kit (Roche) and analyzer (e801) as the test listed in the Mayo Catalog as "Ultrasensitive PSA." 

Patient Preparation: Avoid palpation of the prostate for two days before testing.

Specimen Requirements

Container Type:

Optimal: Gold or Mint*

*For STAT requests

Acceptable: Red or Green
Optimal Collection Volume: 

4.5mL; full tube
Minimum Volume:

1 mL whole blood
Collection Instructions:

Gently invert the sample 5-6 times after collection.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. If serum, allow the specimen to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container.

4. Keep serum or plasma refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum* Refrigerated 5 days
Frozen 6 months

*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.

Specimen Rejection Criteria

Hemolysis Mild OK; Moderate OK; Gross Reject
Lipemia Mild OK; Moderate OK; Gross Reject
Icterus Mild OK; Moderate OK; Gross Reject
Other Quantity not sufficient

Useful For

PSA screening

Methodology

Roche Cobas - Electrochemiluminescence assay

 

Note: Values from different methods may give different results and cannot be used interchangeably.

Reference Ranges

Males

Age (years)

 Median (ng/mL)

Upper 2SD Range (ng/mL)

< 40

 0.6

1.4

40-49

0.6

2.0

50-59

0.8

3.1

60-69

1.7

4.1

> 69

1.7

4.4

 

Females

Not applicable

Interpretive

SPSA - Clinical & Interpretive: Prostate-Specific Antigen (PSA) Screen, Serum (mayocliniclabs.com)

Day(s) Performed

24/7

Expected TAT

Same day

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo

Sample Retention Time

7 days

CPT Code

G0103

LOINC Code

83112-3