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Test Code PSAM or LAB2390 Total Prostate-Specific Antigen, Monitoring, Serum or Plasma

Important Note

Total Prostate-Specific Antigen has two order codes based on the order diagnosis of the patient. PSAM (LAB2390) should be ordered for patients who have a history of diagnosed prostate cancer or prior elevated PSA result(s).

  • For routine screening on patients with no history of prostate cancer or elevated PSA result(s), please order PSAS (LAB2391). 

Methodology note: Total PSA is performed on the same reagent kit (Roche) and analyzer (e801) as the test listed in the Mayo Catalog as "Ultrasensitive PSA." 

Patient Preparation: Avoid palpation of the prostate for two days before testing.

Specimen Requirements

Container Type:

Optimal: Gold or Mint*

*For STAT requests

Acceptable: Red or Green
Optimal Collection Volume: 

4.5mL; full tube
Minimum Volume:

1 mL whole blood
Collection Instructions:

Gently invert the sample 5-6 times after collection.
Specimen Transport:

Refrigerate
Processing Instructions: 

1. If serum, allow the specimen to clot for 30 minutes.

2. Centrifuge specimen within 2 hours of collection.

3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container.

4. Keep serum or plasma refrigerated until testing can be performed.

Specimen Stability

Specimen Type Temperature Time
Serum* Refrigerated 5 days
Frozen 6 months

*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.

Specimen Rejection Criteria

Hemolysis Mild OK; Moderate OK; Gross Reject
Lipemia Mild OK; Moderate OK; Gross Reject
Icterus Mild OK; Moderate OK; Gross Reject
Other Quantity not sufficient

Useful For

PSA monitoring

Methodology

Roche Cobas - Electrochemiluminescence assay

 

Note: Values from different methods may give different results and cannot be used interchangeably.

Reference Ranges

Males

Age (years)

 Median (ng/mL)

Upper 2SD Range (ng/mL)

< 40

 0.6

1.4

40-49

0.6

2.0

50-59

0.8

3.1

60-69

1.7

4.1

> 69

1.7

4.4

 

Females

Not applicable

Interpretive

PSA - Clinical & Interpretive: Prostate-Specific Antigen (PSA) Diagnostic, Serum (mayocliniclabs.com)

Day(s) Performed

24/7

Expected TAT

Same day

Performing Laboratory

Bronson Laboratory, Chemistry - Kalamazoo

Sample Retention Time

7 days

CPT Code

84153

LOINC Code

83112-3