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Test Code PREX Exchange Transfusion, Neonatal

Important Note

Call Blood Bank at 269-341-6444 as soon as maternal delivery is
anticipated and for specimen requirements as needed. Give total volume needed for exchange. Provide as much advance notice as possible. Turnaround time is usually 2 to 6 hours depending on availability of fresh, compatible blood.

Specimen Required

Patient Preparation:

 

Container Type:

Optimal:  Pink Top (EDTA)--mother

                Lavender microtainer (EDTA)--infant

         

Acceptable:  Lavender mother

Optimal Collection Volume: 

Whole Blood

Mother 6mL

Infant 1.5mL

Collection Instructions:

Collect specimen and gently invert several times to mix. Label the specimen, in the presence of the patient, with full name, date of birth and patient medical record number. 

Processing Instructions: 

1. Collect sample in pink top or lavender container.

2. Label per policy in the presence of the patient.

3. Send whole blood sample to Blood Bank for testing.

Useful For

The treatment of excessively high levels of unconjugated bilirubin (hyperbilirubinemia) and the prevention of irreversible damage due to kernicterus.

Profile Information

Test ID   Reporting Name Available Separately Always Performed
MIW Mother Infant Workup Yes Yes

 

Method Name

Fresh, washed red cells are combined with fresh frozen plasma to
yield a 45% to 55% hematocrit unit of requested volume.

Stability Information

Specimen Type Temperature Time
  Refrigerated 3 days
  Ambient  1 day

Rejection Due To

Hemolysis Mild OK; Moderate OK; Gross Reject
Lipemia Mild OK; Moderate OK; Gross Reject
Icterus Mild OK; Moderate OK; Gross Reject
Other N/A

 

Specimen Minimum Volume

Collecting minimum volumes can result in a need for sample recollection, and/or a delay in results. Minimum volumes are subjective and cannot account for all aspects of specimen and testing needs. Refer to the Specimen Required section for optimal volumes for laboratory specimens. Contact the Bronson Laboratory if complex collection exceptions occur that require more information.

 

Minimum Volume: 1.0 mL whole blood
Neonate Volume: 0.5 mL whole blood

Performing Laboratory

Bronson Laboratory, Blood Bank-Kalamazoo

Day(s) Performed

24/7

Specimen Retention Time

Blood Bank specimens (other than Cord Blood) are retained in the Blood Bank for 30 days. Pretransfusion testing should be completed on specimens within 2 days of collection.