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HelpTest Code LIVER or LAB20 Hepatic Function Panel, Serum or Plasma
Profile Information
| Test ID | Reporting Name | Available Separately? | Always Performed? |
|---|---|---|---|
| ALB | Albumin | Y | Y |
| ALKP | Alkaline Phosphatase | Y | Y |
| AST | AST | Y | Y |
| ALT | ALT | Y | Y |
| TBIL | Bilirubin, Total | Y | Y |
| DBILI | Bilirubin, Direct | Y | Y |
| TP | Protein, Total | Y | Y |
Specimen Requirements
| Container Type: |
Optimal: Gold or Mint* *For STAT requests |
|
Acceptable: Red or Green |
|
| Optimal Collection Volume: |
4.5 mL; full tube |
| Specimen Minimum Volume: |
|
| Collection Instructions: |
Gently invert sample 5-6 times after collection. Note: The specimen should be protected from light |
| Specimen Transport: |
Refrigerate |
| Processing Instructions: |
1. If serum, allow the sample to clot for 30 minutes. 2. Centrifuge specimen within 2 hours of collection. 3. After centrifugation, specimen tubes without a gel barrier should have the serum or plasma aliquoted to a false bottom container. 4. Keep serum/plasma refrigerated until testing can be performed. |
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum* | Refrigerated | 7 days |
| Room Temperature | 3 days | |
| Frozen | 2 months |
*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.
Specimen Rejection Criteria
| Hemolysis | Mild OK; Moderate OK; Gross Reject |
| Lipemia | Mild OK; Moderate OK; Gross Reject |
| Icterus | Mild OK; Moderate OK; Gross Reject |
| Other | Quantity not sufficient |
Useful For
Screening for hepatic inflammation.
Methodology
Roche Cobas - Spectrophotometric
Reference Ranges
| Test ID | Reference Range and Reporting Units |
|---|---|
| ALB | 3.5-5.0 g/dL |
| ALT | Male: 6-45 U/L |
| Female: 6-37 U/L | |
| DBILI | 0.0-0.3 mg/dL |
Age-Specific Reference Ranges for ALKP, AST, TBIL, and TP
ALKP
Note: Reference ranges were revised on 1/5/2022. Please see the December 2021 LabWire for details.
Male & Female
| Age | Reference Range and Reporting Units |
|---|---|
| 0 - 14 day | 83-248 U/L |
| 15 days to less than 1 year | 122-469 U/L |
| 1 year to less than 10 years | 142-335 U/L |
| 10 years to less than 13 years | 129-417 U/L |
Male
| Age | Reference Range and Reporting Units |
|---|---|
| 13 to less than 15 years | 116-468 U/L |
| 15 to less than 17 years | 82-331 U/L |
| 17 to less than 19 years | 55-149 U/L |
| > 19 years | 40-129 U/L |
Female
| Age | Reference Range and Reporting Units |
|---|---|
| 13 to less than 15 years | 57-254 U/L |
| 15 to less than 17 years | 50-117 U/L |
| > 17 years | 35-117* U/L |
*Updated from 35-104 U/L in October 2022
AST
| Age | Reference Range and Reporting Units |
|---|---|
| Newborn to 1 month | 20-80 U/L |
| 1 month to 13 years | 8-60 U/L |
| Adults (> 13 years) | 0-37 U/L |
TBIL
| Age | Reference Range and Reporting Units |
|---|---|
| Adults and children (> 3 months) | < 1.2 mg/dL |
| 0 to 1 day | 2.0-6.0 mg/dL |
| 1 to 3 days | 6.0-10.0 mg/dL |
| 3 days to 1 month | 4.0-8.0 mg/dL |
| 1 month up to 3 months | 0.0-1.2 mg/dL |
TBIL Critical Value: > 18 mg/dL for infants < 3 months
TP
| Age | Reference Range and Reporting Units |
|---|---|
| Newborn to 1 week | 4.6-7.0 g/dL |
| 1 week to 7 months | 4.4-7.6 g/dL |
| 7 months to 1 year | 5.1-7.3 g/dL |
| 1-2 years | 5.6-7.5 g/dL |
| 3-18 years | 6.0-8.0 g/dL |
| Adult (ambulatory) | 6.4-8.3 g/dL |
Day(s) Performed
24/7
Expected TAT
Same day
Performing Laboratory
Bronson Laboratory, Chemistry - Kalamazoo, Battle Creek, Paw Paw, South Haven
Sample Retention Time
7 days
CPT Code
80076
LOINC Code
24325-3