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Test Code SOMIS-;Prions Disease CSF Panel 14-3-3, TAU Protein, RT-QUiC CSF Panel

Important Note

Provider is required to complete the Test requisition form before sample will be sent for testing. 

Form can be found at the link below:

https://case.edu/medicine/pathology/sites/default/files/2024-06/Test%20Request%20Form.pdf

Please call BMH sendout department with any questions regarding testing. 

BMH Sendouts Number: 269-341-8488

 

Infectious

Specimen Requirements

  • Collect 2-5 ml of CSF in a sterile container. 
  • DO NOT USE TUBE 1 FOR TESTING, Red blood cell contamination can affect results. 
  • Minimum volume 2 mls.
  • aliquot into sterile tube and freeze imediateley. 
    • Use sterile red screw top tube found with sendout Mayo supplies.

Useful For

In CSF: Search for the presence of the 14-3-3 protein. The 14-3-3 protein is a marker for some prion diseases, such as Creutzfeldt-Jakob disease (CJD), when a number of other neurodegenerative conditions are excluded.

Shipping instructions (BMH Sendouts only)

Samples should be sent out by BMH Sendout department.

SAMPLE MUST BE SHIPPED ON DRY ICE, MAIL ONLY MONDAY-THURSDAY. 

  • Samples that are collected Friday-Sunday will be held in the freezer and shipped on Monday.

Methodology

Immunoassay • RT-QuIC

Expected TAT

Report available: 7 days

Performing Laboratory

National Prion Disease Pathology Surveillance Center

CPT Code

0035U, 83520 (x2)