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HelpTest Code PR3G or LAB2808 Proteinase 3 IgG, Serum
Specimen Requirements
| Container Type: |
Optimal: Gold Acceptable: Red
|
| Optimal Collection Volume: |
4.5mL; full tube |
| Minimum Volume: |
1 mL |
| Collection Instructions: |
Gently invert the sample 5-6 times after collection. |
| Specimen Transport: |
Refrigerate |
| Processing Instructions: |
1. Allow the specimen to clot for 30 minutes. 2. Centrifuge specimen within 2 hours of collection. 3. After centrifugation, specimen tubes without a gel barrier should have the serum aliquoted to a false bottom container. 4. Keep serum refrigerated until testing can be performed. |
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated | 7 days |
| Room Temperature | 8 hours |
Specimen Rejection Criteria
| Hemolysis | Mild OK; Moderate OK; Gross Reject |
| Lipemia | Mild OK; Moderate OK; Gross Reject |
| Icterus | Mild OK; Moderate OK; Gross Reject |
| Other | Quantity not sufficient |
Useful For
The test is useful for evaluating patients with vasculitis, including suspected Wegener granulomatosis.
Methodology
Bio-Rad BioPlex 2200: Multiplex flow immunoassay
Reference Ranges
| Test ID | Reference Range and Reporting Units |
|---|---|
| PR3G | Negative: < 1.0 AI |
| Positive: > 1.0 AI |
AI = Antibody Index
Interpretive
PR3 - Clinical & Interpretive: Proteinase 3 Antibodies, IgG, Serum (mayocliniclabs.com)
Day(s) Performed
Monday through Friday
Expected TAT
Same day or 1-2 days
Performing Laboratory
Bronson Laboratory, Chemistry - Kalamazoo
Sample Retention Time
7 days
CPT Code
83516
LOINC Code
74106-6