Test Code OPATM Opiate Confirmation, Meconium
Reporting Name
Opiate Confirmation, MUseful For
Detection of maternal prenatal opiate/opioid use up to 5 months before birth
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory

Specimen Type
MeconiumAdvisory Information
For chain-of-custody testing, order OPTMX / Opiate Confirmation, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container. Small (Random), 4 oz (T288)
Container/Tube: Stool container (T288)
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Specimen Minimum Volume
0.3 g (approximately 1/4 teaspoon)
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Meconium | Frozen (preferred) | 28 days | |
Refrigerated | 28 days | ||
Ambient | 14 days |
Reject Due To
Other | Grossly bloody reject; Pink OK Stool Diapers |
Reference Values
Negative
Positives are reported with a quantitative LC-MS/MS result.
Cutoff concentrations
Codeine by LC-MS/MS: 50 ng/g
Hydrocodone by LC-MS/MS: 50 ng/g
Hydromorphone by LC-MS/MS: 50 ng/g
Morphine by LC-MS/MS: 50 ng/g
Oxycodone by LC-MS/MS: 50 ng/g
Oxymorphone by LC-MS/MS: 50 ng/g
Day(s) and Time(s) Performed
Monday through Sunday; Varies
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80361
80365
G0480 (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
OPATM | Opiate Confirmation, M | 69026-3 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
31848 | Morphine | 69027-1 |
31850 | Oxymorphone | 69028-9 |
31849 | Hydromorphone | 68541-2 |
31847 | Codeine | 68542-0 |
31852 | Oxycodone | 68543-8 |
31851 | Hydrocodone | 68544-6 |
31868 | Interpretation | 8215-6 |
31869 | Chain of Custody | 77202-0 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.