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Test Code OPATM Opiate Confirmation, Meconium

Reporting Name

Opiate Confirmation, M

Useful For

Detection of maternal prenatal opiate/opioid use up to 5 months before birth

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Meconium


Advisory Information


For chain-of-custody testing, order OPTMX / Opiate Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container. Small (Random), 4 oz (T288)

Container/Tube: Stool container (T288)

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Meconium Frozen (preferred) 28 days
  Refrigerated  28 days
  Ambient  14 days

Reject Due To

Other Grossly bloody reject; Pink OK Stool Diapers

Reference Values

Negative

Positives are reported with a quantitative LC-MS/MS result.

Cutoff concentrations

Codeine by LC-MS/MS: 50 ng/g

Hydrocodone by LC-MS/MS: 50 ng/g

Hydromorphone by LC-MS/MS: 50 ng/g

Morphine by LC-MS/MS: 50 ng/g

Oxycodone by LC-MS/MS: 50 ng/g

Oxymorphone by LC-MS/MS: 50 ng/g

Day(s) and Time(s) Performed

Monday through Sunday; Varies

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80361

80365

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OPATM Opiate Confirmation, M 69026-3

 

Result ID Test Result Name Result LOINC Value
31848 Morphine 69027-1
31850 Oxymorphone 69028-9
31849 Hydromorphone 68541-2
31847 Codeine 68542-0
31852 Oxycodone 68543-8
31851 Hydrocodone 68544-6
31868 Interpretation 8215-6
31869 Chain of Custody 77202-0

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.