Test Code IGGSC IgG Subclasses, Serum
Additional Codes
Mayo Code |
---|
IGGS |
Epic Code |
LAB2198 |
Sunquest Code |
IGGSC |
Reporting Name
IgG Subclasses, SUseful For
Second-order testing for evaluation of patients with clinical signs and symptoms of humoral immunodeficiency or combined immunodeficiency (cellular and humoral)
Testing Algorithm
Testing includes total immunoglobulin G (IgG) as well as the 4 subclasses of IgG.
See Celiac Disease Diagnostic Testing Algorithm in Special Instructions
Method Name
Nephelometry
Performing Laboratory

Specimen Type
SerumAdvisory Information
If testing for immunoglobulin (Ig) G4-related diseases, the more appropriate test to order is IGGS4 / Immunoglobulin Subclass IgG4, Serum.
Specimen Required
Patient Preparation: Fasting preferred but not required
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 1 mL
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 14 days | |
Ambient | 14 days | ||
Frozen | 14 days |
Reject Due To
Gross hemolysis | OK |
Gross lipemia | Reject |
Gross icterus | OK |
Special Instructions
Reference Values
TOTAL IgG
0-<5 months: 100-334 mg/dL
5-<9 months: 164-588 mg/dL
9-<15 months: 246-904 mg/dL
15-<24 months: 313-1,170 mg/dL
2-<4 years: 295-1,156 mg/dL
4-<7 years: 386-1,470 mg/dL
7-<10 years: 462-1,682 mg/dL
10-<13 years: 503-1,719 mg/dL
13-<16 years: 509-1,580 mg/dL
16-<18 years: 487-1,327 mg/dL
≥18 years: 767-1,590 mg/dL
IgG1
0-<5 months: 56-215 mg/dL
5-<9 months: 102-369 mg/dL
9-<15 months: 160-562 mg/dL
15-<24 months: 209-724 mg/dL
2-<4 years: 158-721 mg/dL
4-<7 years: 209-902 mg/dL
7-<10 years: 253-1,019 mg/dL
10-<13 years: 280-1,030 mg/dL
13-<16 years: 289-934 mg/dL
16-<18 years: 283-772 mg/dL
≥18 years: 341-894 mg/dL
IgG2
0-<5 months: ≤82 mg/dL
5-<9 months: ≤89 mg/dL
9-<15 months: 24-98 mg/dL
15-<24 months: 35-105 mg/dL
2-<4 years: 39-176 mg/dL
4-<7 years: 44-316 mg/dL
7-<10 years: 54-435 mg/dL
10-<13 years: 66-502 mg/dL
13-<16 years: 82-516 mg/dL
16-<18 years: 98-486 mg/dL
≥18 years: 171-632 mg/dL
IgG3
0-<5 months: 7.6-82.3 mg/dL
5-<9 months: 11.9-74.0 mg/dL
9-<15 months: 17.3-63.7 mg/dL
15-<24 months: 21.9-55.0 mg/dL
2-<4 years: 17.0-84.7 mg/dL
4-<7 years: 10.8-94.9 mg/dL
7-<10 years: 8.5-102.6 mg/dL
10-<13 years: 11.5-105.3 mg/dL
13-<16 years: 20.0-103.2 mg/dL
16-<18 years: 31.3-97.6 mg/dL
≥18 years: 18.4-106.0 mg/dL
IgG4
0-<5 months: ≤19.8 mg/dL
5-<9 months: ≤20.8 mg/dL
9-<15 months: ≤22.0 mg/dL
15-<24 months: ≤23.0 mg/dL
2-<4 years: 0.4-49.1 mg/dL
4-<7 years: 0.8-81.9 mg/dL
7-<10 years: 1.0-108.7 mg/dL
10-<13 years: 1.0-121.9 mg/dL
13-<16 years: 0.7-121.7 mg/dL
16-<18 years: 0.3-111.0 mg/dL
≥18 years: 2.4-121.0 mg/dL
Day(s) and Time(s) Performed
Monday through Friday; Continuously
Test Classification
This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82784
82787 x 4
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
IGGS | IgG Subclasses, S | 47289-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
T_IGG | Total IgG | 2465-3 |
IGG1 | IgG 1 | 2466-1 |
IGG2 | IgG 2 | 2467-9 |
IGG3 | IgG 3 | 2468-7 |
IGG4 | IgG 4 | 2469-5 |
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.