Test Code FFCAH Congenital Adrenal Hyperplasia (CAH) Pediatric Profile 6, Comprehensive Screen
Specimen Required
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 3.5 mL Serum
Collection Instructions:
1. Within 45 minutes of collection, centrifuge and aliquot serum into a plastic vial.
2. Send frozen.
Additional Information: To avoid delays in turnaround time when requesting multiple tests, submit separate frozen specimens for each test requested.
Reporting Name
CAH Profile 6Specimen Type
Serum RedSpecimen Minimum Volume
Serum: 2 mL Note: This volume does not allow for repeat testing.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Frozen | 90 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icteric | Reject |
Reference Values
Androstenedione:
Premature (26-28 weeks) Day 4: 63-935 ng/dL
Premature (31-35 weeks) Day 4: 50-449 ng/dL
Full Term (1-7 days): <10-279 ng/dL
Levels decrease rapidly to <52 ng/dL after one week.
1 month-11 months: <10-37 ng/dL
Androstenedione gradually decreases during the first six months to prepubertal levels.
Prepubertal Children: <10-17 ng/dL
Adults
Males: 44-186 ng/dL
Females: 2 -230 ng/dL
Females Postmenopausal: <10-93 ng/dL
Cortisol:
Premature (26-28 weeks) Day 4: 1.0-11 ug/dL
Premature (31-35 weeks) Day 4: 2.5-9.1 ug/dL
Full Term Day 3: 1.7-14 ug/dL
Full Term Day 7: 2.0-11 ug/dL
31 days-11 months: 2.8-23 ug/dL
12 months-15 years (8 a.m.): 3.0-21 ug/dL
Adults
8 a.m.: 8.0-19 ug/dL
4 p.m.: 4.0-11 ug/dL
Deoxycorticosterone (DOC):
Premature (26-28 weeks) Day 4: 20-105 ng/dL
Premature (34-36 weeks) Day 4: 28-78 ng/dLNewborn: Levels are markedly elevated at birth and decrease rapidly during the first week to the range of 7-49 ng/dL as found in older infants.
1 month-11 months: 7-49 ng/dL
Prepubertal Children: 2-34 ng/dL
Pubertal Children and Adults 8 a.m.: 2-19 ng/dL
Dehydroepiandrosterone (DHEA):
Premature (26-31 weeks): 82-1484 ng/dL
Premature (32-35 weeks): 56-1853 ng/dL
Full Term (2-7 days): 41-1292 ng/dL
8 days-5 months: <948 ng/dL
6 months-12 months: <136 ng/dL
1 year-5 years: <68 ng/dL
6-7 years: <111 ng/dL
8-10 years: <186 ng/dL
11-12 years: <202 ng/dL
13-14 years: <319 ng/dL
15-16 years: 39-481 ng/dL
17-19 years: 40-491 ng/dL
20-50 years: 31-701 ng/dL
>50 years: 21-402 ng/dL
11-Desoxycortisol:
Premature (26-28 weeks) Day 4: 110-1376 ng/dL
Premature (31-35 weeks) Day 4: 48-579 ng/dL
Full term Newborn Day 3: 13-147 ng/dL
1 month-11 months: <10-156 ng/dL
Prepubertal 8 a.m.: 20-155 ng/dL
Pubertal Children and Adults 8 a.m.: 12-158 ng/dL
17-OH Pregnenolone:
Premature (26-28 weeks) Day 4: 375-3559 ng/dL
Premature (31-35 weeks) Day 4: 64-2380 ng/dL
3 days: 10-829 ng/dL
1 month-5 months: 36-763 ng/dL
6-11 months: 42-540 ng/dL
12-23 months: 14-207 ng/dL
24 months-5 years: 10-103 ng/dL
6-9 years: 10-186 ng/dL
Pubertal: 44-235 ng/dL
Adults: 53-357 ng/dL
Progesterone:
Males
1 year-16 years: <10-15 ng/dL
Adults: <10-11 ng/dL
Females
1 year-10 years: <10-26 ng/dL
11 years: <10-255 ng/dL
12 years: <10-856 ng/dL
13 years: <10-693 ng/dL
14 years: <10-1204 ng/dL
15 years: <10-1076 ng/dL
16 years: <10-1294 ng/dL
Adult
Cycle days
1-6: <10-17 ng/dL
7-12: <10-135 ng/dL
13-15: <10-1563 ng/dL
16-28: <10-2555 ng/dL
Post Menopausal: <10 ng/dL
Note: Luteal progesterone peaked from 350 to 3750 ng/dL on days ranging from 17 to 23.
17-Alpha-Hydroxyprogesterone (17-OHP):
Premature (26-28 weeks) Day 4: 124-841 ng/dL
Premature (31-35 weeks) Day 4: 26-568 ng/dL
Full-Term Day 3: <78 ng/dL
Males:
Levels increase after the first week to peak values ranging from 40-200 ng/dL between 30 and 60 days. Values then decline to a prepubertal value of <91 ng/dL before one year.
Prepubertal: <91 ng/dL
Adult: 27-199 ng/dL
Females:
1 month-11 months: 13-106 ng/dL
Prepubertal: <91 ng/dL
Adult:
Follicular: 15-70 ng/dL
Luteal: 35-290 ng/dL
Testosterone, Total
Males:
Premature (26-28w) Day 4: 59-125 ng/dL
Premature (31-35w) Day 4: 37-198 ng/dL
Newborns: 75-400 ng/dL
1 month-7 months: Levels decrease rapidly the first week to 20-50 ng/dL, then increase to 60-400 ng/dL between 20 and 60 days. Levels then decline to prepubertal range levels of <2.5-10 ng/dL by seven months.
Females:
Premature (26-28w) Day 4: 5-16 ng/dL
Premature (31-35w) Day 4: 5-22 ng/dL
Newborns: 20-64 ng/dL
1 month-7 months: Levels decrease during the first month to less than 10 ng/mL and remain there until puberty.
Prepubertal Males and Females: <2.5-10 ng/dL
Adult
Males >18 years: 264-916 ng/dL
Females:
Premenopausal: 10-55 ng/dL
Postmenopausal: 7-40 ng/dL
Males
Tanner Stage 1 <9.8 years: <2.5-10 ng/mL
Tanner Stage 2 9.8 years-14.5 years: 18-150 ng/mL
Tanner Stage 3 10.7 years-15.4 years: 100-320 ng/mL
Tanner Stage 4 11.8 years-16.2 years: 200-620 ng/mL
Tanner Stage 5 12.8 years-17.3 years: 350-970 ng/mL
Females
Tanner Stage 1 <9.2 years: <2.5-10 ng/mL
Tanner Stage 2 9.2-13.7 years: 7-28 ng/mL
Tanner Stage 3 10.0-14.4 years: 15-35 ng/mL
Tanner Stage 4 10.7-15.6 years: 13-32 ng/mL
Tanner Stage 5 11.8-18.6 years: 20-38 ng/mL
Day(s) Performed
Monday, Wednesday
Report Available
10 to 19 daysPerforming Laboratory
Esoterix EndocrinologyCPT Code Information
82633 - DOC
82634 - 11-Desoxycortisol
82157 - Androstenedione
82533 - Cortisol
82626 - DHEA
84143 - 17-OH-Pregnenolone
84144 - Progesterone
83498 - 17-OH-Progesterone
84403 - Testosterone
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FFCAH | CAH Profile 6 | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z5043 | Cortisol | 2143-6 |
| Z5044 | Deoxycorticosterone (DOC) | 1656-8 |
| Z5045 | 11-Desoxycortisol | 1657-6 |
| Z5046 | Dehydroepiandrosterone (DHEA) | 2193-1 |
| Z5047 | 17-OH Pregnenolone | 6765-2 |
| Z5048 | Progesterone | 2839-9 |
| Z5049 | 17-Alpha-Hydroxyprogesterone 17-OHP | 1668-3 |
| Z5050 | Androstenedione | 1854-9 |
| Z5051 | Testosterone, Total | 2986-8 |