Test Code CNSA Central Nervous System Consultation, Autopsy, Varies
Shipping Instructions
Ship specimen using the Central Nervous System Consult Kit (T633).
Necessary Information
It is imperative that detailed clinical information and, when possible, operative notes and radiographs accompany the specimen.
Specimen Required
Hematoxylin-and-eosin stained sections are also acceptable, but must be accompanied by paraffin blocks and/or remaining wet tissue.
In cases submitted as part of a research protocol, contact 507-284-3887 for further guidance.
Supplies: Central Nervous System Consult Kit (T633)
Sources: Brain (and spinal cord when indicated)
Container/Tube: Plastic container
Specimen Volume: 1 cm(3) cube
Collection Instructions:
1. Take a small (1 cm[3]) cube of brain from 1 of the frontal lobes (typically, right inferior frontal).
2. Wrap in aluminum foil and place in plastic container.
3. Label container with identifying information (ie, patient name, date of birth, autopsy number, and date of collection).
4. Freeze and store in a -70° C freezer.
5. Place the remaining brain in 10% formalin if non-Creutzfeldt-Jakob disease (CJD), and 15% formalin for suspected cases of CJD, suspended by a thread under the basilar artery and fixed for 7 to 10 days.
Additional Information: Upon completion of consultation, the brain tissue will be stored 10 years in the Mayo Clinic Tissue Registry. The Mayo Clinic policy precludes our evaluation of cases under litigation that involve non-Mayo Clinic patients.
Forms
The following are available:
-Submitting Non-Protocol Autopsy Brain/Spinal Cord for Examination
OR
-Submitting Brain for Neuropathologic Examination: Cases Suspected of Creutzfeldt-Jakob Disease (CJD)
Useful For
Evaluation of congenital neurological disease
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Evaluation of neurodegenerative disease
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Evaluation of cases with a complex neurological or neurosurgical history
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Evaluation of sudden unexplained death
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This test is not intended for cases under litigation without preauthorization.
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
NERPC | Necropsy, regional | No | No |
NESPC | Necropsy, single organ | No | No |
Testing Algorithm
When only a brain is submitted, NESPC / Necropsy, single organ (Bill Only) will be charged.
When both a brain and spinal cord are submitted, NERPC / Necropsy, regional (Bill Only) will be charged.
Special Instructions
Reporting Name
Neuropathology ConsultSpecimen Type
VariesSpecimen Minimum Volume
Entire collection
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Varies | Ambient (preferred) | ||
Frozen | |||
Refrigerated |
Reject Due To
No specimen should be rejected.Reference Values
An interpretive report will be provided.
Day(s) Performed
Monday through Friday
Report Available
30 to 60 daysPerforming Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
88037 (if appropriate)
88036 (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CNSA | Neuropathology Consult | 18743-5 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
71070 | Interpretation | 18743-5 |
71071 | Participated in the Interpretation | No LOINC Needed |
71072 | Report electronically signed by | 19139-5 |
71073 | Addendum | 35265-8 |
71074 | Gross Description | 22634-0 |
71075 | Material Received | 22633-2 |
71589 | Disclaimer | 62364-5 |
71795 | Case Number | 80398-1 |