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HelpTest Code ALDST Aldosterone, Serum
Additional Codes
| Mayo Test ID |
|---|
| ALDS |
| Epic Code |
| LAB557 |
| LIS Code |
| ALDST |
Reporting Name
Aldosterone, SUseful For
Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome)
Testing Algorithm
For more information see Steroid Pathways
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumPM collections can lower result values by 30% compared to collections performed in the AM. Preferred collection time is between the hours of 08:00 and 10:00 AM.
If Renin is also ordered, both samples should be from the same collection time. See test Renin Activity, Plasma for separate specimen requirements.
Specimen Required
Patient Preparation: Spironolactone (Aldactone) should be discontinued for 4 to 6 weeks before testing. The plasma renin activity cannot be interpreted if the patient is being treated with spironolactone.
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1.2 mL
Collection Instructions:
1. See Renin-Aldosterone Studies for detailed instructions.
2. The recommended collection time is 8 a.m., after the patient is active for approximately 2 hours. Try to collect the specimen as close to that time as possible and no later than 10 a.m.
3. Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
1.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Frozen | 30 days | ||
| Ambient | 4 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Special Instructions
Reference Values
0-30 days: 17-154 ng/dL*
31 days-11 months: 6.5-86 ng/dL*
1-10 years:
≤40 ng/dL (supine)*
≤124 ng/dL (upright)*
≥11 years: ≤21 ng/dL (a.m. peripheral vein specimen)
*Loeuille GA, Racadot A, Vasseur P, Vandewalle B: Blood and urinary aldosterone levels in normal neonates, infants and children. Pediatrie 1981 Jul-Aug;36(5):335-344
For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html
PM collections can lower result values by 30% compared to collections performed in the AM. Preferred collection time is between the hours of 08:00 and 10:00 AM.
If Renin is also ordered, both samples should be from the same collection time. See test Renin Activity, Plasma for separate specimen requirements.
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82088
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ALDS | Aldosterone, S | 1763-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8557 | Aldosterone, S | 1763-2 |
Report Available
2 to 5 daysForms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-General Request (T239)
-Cardiovascular Test Request (T724)