Test Code URIC Uric Acid, Plasma or Serum
Performing Laboratory
Bronson Laboratory Services-Chemistry
Reference Values
2.5-8.0 mg/dL
Methodology
Spectrophotometric
Specimen Requirements
Submit only 1 of the following specimens:
Preferred
Specimen Type: Serum
Container/Tube: Gold-top serum gel-Red top is
acceptable
Specimen Volume: 5 mL
Specimen Minimum Volume: 1 mL
Alternate
Specimen Type: Plasma
Container/Tube: Green top (heparin)-Mint-top
plasma gel is acceptable
Specimen Volume: 5 mL
Specimen Minimum Volume: 1 mL
Special collection instructions (Elitek):
Please note: If the patient is on the
medication Elitek (Rasburicase), the following collection
instructions apply:
The drug Elitek (Rasburicase) is used for leukemia and
lymphoma patients on chemotherapy. When the
chemotherapy kills the cells, a breakdown product of all the
nuclear cellular material is uric acid. The
uric acid levels
can get high enough to cause kidney damage. The
drug Elitek causes the uric acid to break down to a harmless
substance (allantoin). Therapy on these patients is
closely monitored by performing multiple uric acid
levels. What this means for the
lab:
The drug continues to break down uric acid after the sample has
been drawn. This can cause falsely low results. For this
reason, there are special sample handling requirements
for these uric acid
levels:
1) Draw in a prechilled green top
(non gel)
tube.
2) Put on ice immediately and
transport to ice in
lab.
3) Centrifuge in refrigerated
centrifuge (temp set to 4C) behind accession.
4) Separate plasma and keep on ice
until tested. Must be tested within 4 hours when kept on
ice.
Specimen Transport Temperature
Refrigerate
Specimen Stability (non-Elitek samples)
Specimen Type |
Temperature |
Time |
Serum* |
Refrigerated |
7 days |
Ambient |
7 days |
|
Frozen |
2 months |
*Note: Heparinized plasma in gel separator tubes is less stable than serum and is only suitable for add-on testing up to 2 days following sample collection.
Day(s) Test Set Up
Monday through Sunday
Test Classification and CPT Coding
84550