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Test Code FSC Fungal Antibody Survey, Spinal Fluid

Reporting Name

Fungal Ab Survey, CSF

Useful For

Rapid screening for fungal meningitis when evidence for a specific organism is lacking

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
CCRYR Cryptococcus Ag, CSF Yes No

Testing Algorithm

If Cryptococcus antigen screen result is reactive (by EIA), then latex agglutination testing (CCRYR/28072 Cryptococcus Antigen, Spinal Fluid) will be performed at an additional charge.

Method Name

CCOC: Complement Fixation (CF) Using Coccidioidin: IgG/Immunodiffusion: IgG and IgM

CCRYP, CBLAS: Enzyme Immunoassay (EIA)

CHIST: Complement Fixation (CF)/Immunodiffusion

CCRYR: Latex Agglutination

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

CSF

Specimen Required

Container/Tube: Sterile vial

Specimen Volume: 3 mL

Specimen Minimum Volume

2.6 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

NA

Icterus

NA

Other

NA

Reference Values

Blastomyces ANTIBODY BY EIA

Negative

 

Coccidioides ANTIBODY

Complement fixation: negative

If positive, results are titered.

Immunodiffusion: negative

Results are reported as positive, negative, or equivocal.

 

Cryptococcus ANTIGEN SCREEN

Negative

If reactive, results are titered under the reflex test.

 

Histoplasma ANTIBODY

Mycelial by complement fixation: negative

Positives are reported as titer.

Yeast by complement fixation: negative

Positives are reported as titer.

Antibody by immunodiffusion: negative

Positives are reported as band present.

Day(s) and Time(s) Performed

Blastomyces antibody: Monday through Friday; Sunday; 11 a.m.

Coccidioides: Monday through Friday; 11 a.m.

Cryptococcus antigen: Monday through Friday; 11 a.m. and 8 p.m., Sat, Sun; 11a.m.

Histoplasma antibody: Monday through Friday; 11 a.m.

CPT Code Information

86612-Blastomyces

86635 x 3-Coccidioides

86698 x 3-Histoplasma

87327-Cryptococcus EIA

86403-Cryptococcus latex agglutination (if appropriate)

LOINC Code Information

Result ID Reporting Name LOINC Code
CBLAS Blastomyces Ab, EIA, CSF 18197-4
86166 Cryptococcus Ag Screen, CSF 29896-8
81542 Cocci Ab, CF (CSF) 30209-1
15118 Histoplasma Mycelial (CSF) 27220-3
15119 Histoplasma Yeast (CSF) 27209-6
21002 Cocci ID-IgG (CSF) In Process
21001 Cocci ID-IgM (CSF) In Process
15120 Histoplasma Immunodiffusion (CSF) 21330-6

Profile Information

Test ID Reporting Name Available Separately Always Performed
CCOC Cocci CF and ID, CSF Yes Yes
CCRYP Cryptococcus Ag Screen, CSF Yes Yes
CHIST Histoplasma Ab, CSF Yes Yes
CBLAS Blastomyces Ab, EIA, CSF Yes Yes